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A modular flow-chamber bioreactor concept as a tool for continuous 2D- and 3D-cell culture

Advanced cell culture models, especially long-term 3D systems, require bioreactors allowing for cultivation under continuous flow conditions. Such culture models are for example tissue engineered implants, 3D cultures for drug testing, in vitro models of cell growth and migration for wound healing studies, cell cultures for biomaterial testing. New challenges in drug testing and biomaterial development arise from regulatory requirements. Animal trials have to be replaced by cell culture assays, preferably by test systems with human material. Standard 2D monolayer cultures are often unsatisfactory and therefore tissue-like 3D cultures are suggested as an alternative. Here the design of a multi-well flow-chamber bioreactor as a tool for manufacturing advanced cell culture models is presented. Advantages of this reactor concept can be seen in constant flow conditions, removal of toxic reaction products, high cell densities, and improved metabolism [1]. The general design of the flow chamber bioreactor (FCBR) can easily be modified for different applications and analytical requirements.

Flow-chamber bioreactor
Flow-chamber bioreactor
A modular flow-chamber bioreactor concept as a tool for continuous 2D- and 3D-cell culture
Poster-Flowchamber
Poster-Flowchamber
A modular flow-chamber bioreactor concept as a tool for continuous 3D-culture

Bioreactors

Bioreactors medorex stirred, Air-lift fermentors and Fluidized-bed bioreactors help you to realize your plans successful!

Product range of medorex bioreactors

Measurement and control Technology

Measurement and control Technology

Measurement and control technology, autoclavable probes, sampling system and pH-measurement for the use in the laboratories of medicine, biotechnology, pharmaceutical and food industry.

medorex solution for measurement and control technology

Media autoclave

Media autoclave

medoclav - a compact media-autoclave with 7 liters working-volumes and integrated stirring-system for the sterilization of nursing-media under high pressure.

"medoClav" an user friendly media autoclave for the cell cultivation and preparation

Peristaltic Pumps

Peristaltic Pumps

The new peristaltic pump generation with an extremely easy tube change. Microprocessor controlled, with a large functional diversity for all applications in analytics, biotechnology, medicine.

User friendly pumps of medorex

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Christmas and New Year

Christmas and New Year

Dear friends and guests,


We wish you a merry christmas and happy new year 2019, accompanied by luck, health, sun in your heart and your life.


For our lovable and old world we wish more peace and more people who treat our earth, our environment, the other creatures of the world and each other with respect and love.


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