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A Novel Conical Shaped Bioreactor for Small-Scale Investigations under Defined Condition

The reliability of metabolic or kinetic data determined in small-scale culture systems is often insufficient, as these systems cannot be run continuously and parameters such as dissolved oxygen and pH are not controlled. Here a new conical shaped bioreactor (medorex, Germany) for the cultivation of animal cells is presented. The reactor can be operated at a volume range of about 50 ml to a maximum volume of 400 ml. The conical shape allows the integration of probes and various tubes even at small volumes. The reactor has all features of a conventional glass reactor with up to 9 openings for inlet, outlet, level control and sampling, temperature sensor, an exhaust air cooler and ports for dissolved oxygen and pH probes. Low shear stress mixing is achieved by a 3- blade propeller stirrer with a diameter of 36 mm. Temperature can be controlled over a water jacket with a conventional water bath via the internal sensor.

The main applications are:
• studies of batch and fed-batch cultures at small scale
• expanding cell cultures in fed-batch under defined conditions (pH, DO)
• long-term continuous cultures at high dilution rates for kinetic studies with low medium consumption.
The reactor can be modified to a fixed-bed reactor of 20 ml packed bed volume for the cultivation of adherent cell lines and testing of different carrier material.

TU Hamburg Vario2
TU Hamburg Vario2
A Novel Conical Shaped Bioreactor for Small-Scale Investigations under Defined Conditions.

Bioreactors

Bioreactors medorex stirred, Air-lift fermentors and Fluidized-bed bioreactors help you to realize your plans successful!

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Measurement and control Technology

Measurement and control Technology

Measurement and control technology, autoclavable probes, sampling system and pH-measurement for the use in the laboratories of medicine, biotechnology, pharmaceutical and food industry.

medorex solution for measurement and control technology

Media autoclave

Media autoclave

medoclav - a compact media-autoclave with 7 liters working-volumes and integrated stirring-system for the sterilization of nursing-media under high pressure.

"medoClav" an user friendly media autoclave for the cell cultivation and preparation

Peristaltic Pumps

Peristaltic Pumps

The new peristaltic pump generation with an extremely easy tube change. Microprocessor controlled, with a large functional diversity for all applications in analytics, biotechnology, medicine.

User friendly pumps of medorex

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Christmas and New Year

Christmas and New Year

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We wish you a merry christmas and happy new year 2019, accompanied by luck, health, sun in your heart and your life.


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